Liposome definition is an artificial vesicle composed of one or more concentric phospholipid bilayers and used especially to deliver microscopic substances such as drugs or dna to body cells. Publishers pdf, also known as version of record includes final page, issue and. Aqueous compartments enclosed by lipid bilayer membranes. It is claimed that phytosome increases absorption of conventional herbal extracts or isolated active principles both topically as well as orally. Liposomes with modified surfaces have also been developed using several molecules, such as glycolipids or sialic acid. Nanoparticles definition of nanoparticles by medical dictionary. Information and translations of liposome in the most comprehensive dictionary definitions resource on. Download our english dictionary apps available for both ios and android. The ability of liposomes to encapsulate hydrophilic or lipophilic drugs. To find all definitions that include a specific term, enter a word or phrase below. Liposomes as versatile tools tesis doctorals en xarxa. Optical microscopy was used to detect the presence of cholesterol crystals in the lipid dispersions. Delivery meaning in the cambridge english dictionary. Lettris is a curious tetrisclone game where all the bricks have the same square shape but different content.
Lipid rafts lipids and membrane 01052017 on dec 1, 1978 i zsnagy published. Pdf liposomes, sphereshaped vesicles consisting of one or more phospholipid bilayers, were first. Liposomes are lipid membrane particles that serve as vehicles or delivery systems for vaccine antigens. More recently, a similar clarification of the term gas emulsions appeared in the 1993 reference book the language of colloid and interface science. However, the definition of keratin in the dictionary is the protein derived from hair, wool, horn, nails or other similar tissues in animals. Nanoparticles have recently been developed as delivery vehicles for drugs and for gene therapy.
Liposomes are defined as spherical unilamellar or multilamellar lipid vesicles. Particles of very small size that are being exploited increasingly in medicine as in other sciences. The amcalabeled peptides encapsulated in liposomes are separated from unencapsulated amca peptides by passing through a sepharose cl4b column 1. Liposome definition, a microscopic artificial sac composed of fatty substances and used in experimental research of the cell. Tiny aggregates of fatty acids and monoglycerides formed by the detergent action of the bile acids on digested fats so that these materials can be made soluble and absorbed into the lacteals of the intestinal villi. Association definition of association by merriamwebster. One unexpected finding emerging from this research is that nanoparticles of cerium oxide only 5 nanometres in diameter inserted into. A lipid bilayer is a biological membrane consisting of two layers of lipid molecules. Liposome meaning in the cambridge english dictionary. Since the first edition of liposomes a practical approach was published in 1990, liposome technology has become a highly successful and rapidly developing area of preclinical and clinical research.
A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. A lysosome has a specific composition, of both its membrane proteins, and its lumenal proteins. The liposome can be used as a vehicle for administration of nutrients and pharmaceutical drugs. Safety assessment of keratin and keratinderived ingredients. Each lipid molecule, or phospholipid, contains a hydrophilic head and a hydrophobic tail. The nterminus of the peptide is labeled with amca as described. We offer a widget that you can add to your website to let users look up cancerrelated terms. An interesting example of liposome delivery inside cells involves the use of so called.
Vesicles are small spheres of fluid surrounded by a lipid bilayer membrane, and they have roles in transporting molecules within the cell. Liposomal definition and meaning collins english dictionary. Bilayer definition, a structure composed of two molecular layers, especially of phospholipids in cellular membranes. A douche is a device used to introduce a stream of water into the body for medical or hygienic reasons, or the stream of water itself. Different strategies, including polymerps conjugation or encapsulation of the drug in colloidal carriers such as oil dispersions, liposomes and polymeric particles, have been investigated. Pdf liposomes, sphereshaped vesicles consisting of one or more phospholipid bilayers, were first described in the mid60s. Definition of fusion protein nci dictionary of cancer terms. Liposomes, sphereshaped vesicles consisting of one or more.
Micelles definition of micelles by medical dictionary. The nci dictionary of cancer terms features 8,548 terms related to cancer and medicine. For the definition of a legal term, enter a word or phrase below. Lipid definition is any of various substances that are soluble in nonpolar organic solvents such as chloroform and ether, that are usually insoluble in water, that with proteins and carbohydrates constitute the principal structural components of living cells, and that include fats, waxes, phosphatides, cerebrosides, and related and derived compounds. The peoples law dictionary by gerald and kathleen hill publisher fine communications. To make squares disappear and save space for other squares you have to assemble english words left, right, up, down from the falling squares. They are spherical vesicles that contain hydrolytic enzymes that can break down many kinds of biomolecules. Greek words, lipos fat and soma body or structure, meaning a structure in. Here you can find a huge collection of books pharmaceutics, pharmacology, physiology, pharmacognosy, chemistry, microbiology, biotechnology and many more, articles, glossary, formulation of different dosage forms, qcqa related documents, regulatory guidelines. If you ask anyone on the street what a bubble is, they will probably talk about an enclosed volume of air. A liposome is a sphericalshaped vesicle that is composed of one or more phospholipid bilayers, which closely resembles the structure of cell membranes. Douche usually refers to vaginal irrigation, the rinsing of the vagina, but it can also refer to the rinsing of any body cavity. An artificial vessel being free from blood leakage and excellent in antithrombotic properties, having almost smooth inner surface and showing favorable mechanical properties can be obtained within a short period of time by immersing a biologically active substance in a solution capable of setting to gel to give a solution containing the biologically active substance, incorporating this. Liposomes article about liposomes by the free dictionary.
Related words lipid synonyms, antonyms, hypernyms and hyponyms. Lipids contain carbon, hydrogen and oxygen but have far less oxygen proportionally than carbohydrates. Pdf on jan 1, 2014, rukhsana yusaf and others published. Thus, the composition of a keratinderived ingredient cannot be known without composition data from raw material. A phytosome is a complex of a natural active ingredient and a phospholipid mostly lecithin. Modulation of phase transition of thermosensitive liposomes. The discovery of phospholipids spontaneously forming spherical, selfclosed bubbles known as liposomes, upon dispersion in water, ushered a new era in drug delivery technology. A liposome is a spherical vesicle having at least one lipid bilayer. One definition of a vector is that of a carrier it might be an insect like a mosquito that carries and transmits a bacterium or virus, or it might be some agent. Liposomes can be prepared by disrupting biological membranes such as by sonication liposomes are most often composed of phospholipids, especially phosphatidylcholine, but may also include other lipids, such as egg. In an aqueous system, the polar heads of lipids align towards the polar, aqueous environment, while the hydrophobic tails minimize their contact with water and tend to cluster together, forming a vesicle. Liposome drug delivery systems are capable of delivering high drug concentrations, as well as targeted drug delivery. Also known as salvia sclarea, the extract from the clary sage plant not to be confused with common sage leaf has antioxidant properties, although it isnt nearly as well researched as several other plant extracts with antioxidant benefits. Dictionary definition is a reference source in print or electronic form containing words usually alphabetically arranged along with information about their forms, pronunciations, functions, etymologies, meanings, and syntactic and idiomatic uses.
This author defines gas emulsions as wet foams in which the liquid lamellae have thicknesses on the same scale or larger than the bubble. These approaches intend to preserve and improve the dental health. Lipids can be more formally defined as substances such as a fat, oil or wax that dissolves in alcohol but not in water. Mar 21, 20 this site provides you the current and latest information about the field of pharmacy especially on industrial pharmacy. Dictionary definition of dictionary by merriamwebster.
Of course, the dictionary definition often does not tell the whole story, but i think that in this case common usage and formal definition are the same. A microscopic artificial vesicle consisting of an aqueous core enclosed in phospholipid molecules, used to convey vaccines, drugs, or other substances to. Research on liposome technology has progressed from conventional vesicles to secondgeneration liposomes, in which longcirculating liposomes are obtained by modulating the lipid composition, size, and charge of the vesicle. Lamellar dispersion and phase separation of chloroplast membrane lipids by negative staining electron microscopy pdf. The tail regions, being repelled by water and slightly attracted to each other, congregate together. Since liposomes contain water and not air, i think this is a major problem. Lysosomes are specialized vesicles within cells that digest large molecules through the use of hydrolytic enzymes. Sep 29, 2019 liposome plural liposomes biochemistry an aqueous compartment enclosed by a bimolecular membrane, typically of phospholipid. Ingredient dictionary cosmetic ingredient dictionary. Phospholipid molecules consist of an elongated nonpolar hydrophobic structure with a polar hydrophilic structure at one end. Definition of liposomal from the collins english dictionary.
Liposomal definition of liposomal by the free dictionary. Preclinical evaluation of paramagnetic temperature sensitive. Looking for online definition of pdna or what pdna stands for. Phospholipids, the primary building blocks of liposomes, are amphipathic molecules, meaning they have a hydrophilic region e. Liposomes, from greek etymology lipos meaning fat and soma meaning body, are spherical shaped lipid vesicles that have garnered enormous interest due to. Pick a style below, and copy the text for your bibliography.
198 1103 919 1378 343 486 464 1105 1106 648 376 28 1220 606 1569 1135 1223 233 275 117 741 158 1510 798 667 699 1043 440 513 1177 741 608 532 703 399